V-Body platform

A precision-targeted approach integrating next-generation biologics.

Unlocking the delivery with the smallest fragments of antibodies: 15kDA

Valerio Therapeutics is leveraging a new generation of ultra-small antibody therapeutics (15 kDa) capable of accessing previously unreachable targets. These single-domain antibodies (sdAbs) offer:

  • Enhanced tissue penetration – Their reduced size enables superior access to diseased tissues.
  • High specificity & affinity – Designed to bind even the most hidden epitopes.
  • Scalability & flexibility – Fully synthetic, easy to manufacture, and adaptable for multivalency and multispecificity.

This innovative platform represents a paradigm shift in targeted therapy, bringing us closer to precision-guided, highly effective treatments.

Our proprietary platform allows significant time saving to generate an optimal and customized V-Body

Our V-Body platform addresses some of the limitations of sdAbs…

Unparalleled in vitro selection process allowing for tailor-made functional binders

Our v-body proprietary discovery platform enables the rapid identification and optimization of single-domain antibodies with:

  • High affinity & specificity – Designed to selectively bind disease-driving targets.
  • Efficient screening capabilities – Accelerating the development process.
  • Enhanced functionality – Tailored for deep tissue penetration and intracellular delivery.

This fully integrated selection process allows us to generate highly effective and next-generation therapeutic candidates with superior performance in less than 2 months.

Target identification

A unique discovery path: disease <-> target tackling target identification limitations

Traditional drug discovery often faces challenges in identifying and validating optimal therapeutic targets. Leveraging V-Body proprietary discovery platform offers a next-generation target discovery path that:

  • Focuses on disease-specific mechanisms – Ensuring that targets are clinically relevant.
  • Uses advanced computational and experimental models – Enhancing predictive accuracy.
  • Accelerates development timelines – Shortening the path from discovery to clinical application.

By overcoming target identification barriers, we unlock new possibilities for precision medicine.

Two proprietary platforms — V-Body and Chemistry — enabling precise and efficient targeted delivery.

Fully integrated chemistry platform

Next-generation linker and payload chemistry enabling customized drug conjugation and optimized release at the target site.

Our science

Two proprietary platforms — V-Body and Chemistry — enabling precise and efficient targeted delivery.